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Park Y, Korzun T, Moses AS, Singh P, Levasseur PR, Demessie AA, Sharma KS, Morgan T, Raitmayr CJ, Avila U, Sabei FY, Taratula OR, Marks DL, Taratula O. Targeted Nanocarriers for Systemic Delivery of IRAK4 Inhibitors to Inflamed Tissues. Small. 2024 Jan;20(4):e2306270. doi: 10.1002/smll.202306270. Epub 2023 Sep 13. PubMed PMID: 37702136; PubMed Central PMCID: PMC10840923.
Korzun T, Moses AS, Diba P, Sattler AL, Taratula OR, Sahay G, Taratula O, Marks DL. From Bench to Bedside: Implications of Lipid Nanoparticle Carrier Reactogenicity for Advancing Nucleic Acid Therapeutics. Pharmaceuticals (Basel). 2023 Jul 31;16(8). doi: 10.3390/ph16081088. Review. PubMed PMID: 37631003; PubMed Central PMCID: PMC10459564.
Korzun T, Moses AS, Diba P, Sattler AL, Olson B, Taratula OR, Pejovic T, Marks DL, Taratula O. Development and Perspectives: Multifunctional Nucleic Acid Nanomedicines for Treatment of Gynecological Cancers. Small. 2023 Jul 30;:e2301776. doi: 10.1002/smll.202301776. [Epub ahead of print] Review. PubMed PMID: 37518857; PubMed Central PMCID: PMC10827528.
Moses AS, Korzun T, Mamnoon B, Baldwin MK, Myatt L, Taratula O, Taratula OR. Nanomedicines for Improved Management of Ectopic Pregnancy: A Narrative Review. Small. 2023 Jul 20;:e2301873. doi: 10.1002/smll.202301873. [Epub ahead of print] Review. PubMed PMID: 37471169; PubMed Central PMCID: PMC10837845.
Mamnoon B, Moses AS, Sundaram S, Raitmayr CJ, Morgan T, Baldwin MK, Myatt L, Taratula O, Taratula OR. Glutathione-Responsive Methotrexate Polymersomes for Potential Management of Ectopic Pregnancy. Small. 2023 Jul 14;:e2302969. doi: 10.1002/smll.202302969. [Epub ahead of print] PubMed PMID: 37452511; PubMed Central PMCID: PMC10787806.
St Lorenz A, Moses AS, Mamnoon B, Demessie AA, Park Y, Singh P, Taratula O, Taratula OR. A Photoacoustic Contrast Nanoagent with a Distinct Spectral Signature for Ovarian Cancer Management. Adv Healthc Mater. 2023 Apr;12(9):e2202946. doi: 10.1002/adhm.202202946. Epub 2022 Dec 21. PubMed PMID: 36495088; PubMed Central PMCID: PMC10079555.
Taratula O, Taratula OR. Novel Nanoparticle-Based Treatment and Imaging Modalities. Pharmaceutics. 2023 Jan 11;15(1). doi: 10.3390/pharmaceutics15010244. PubMed PMID: 36678873; PubMed Central PMCID: PMC9861272.
Moses AS, Kadam L, St Lorenz A, Baldwin MK, Morgan T, Hebert J, Park Y, Lee H, Demessie AA, Korzun T, Mamnoon B, Alani AWG, Taratula O, Myatt L, Taratula OR. Nano-Theranostic Modality for Visualization of the Placenta and Photo-Hyperthermia for Potential Management of Ectopic Pregnancy. Small. 2023 Jan;19(2):e2202343. doi: 10.1002/smll.202202343. Epub 2022 Nov 17. PubMed PMID: 36394151; PubMed Central PMCID: PMC9839489.
Park Y, Moses AS, Demessie AA, Singh P, Lee H, Korzun T, Taratula OR, Alani AWG, Taratula O. Poly(aspartic acid)-Based Polymeric Nanoparticle for Local and Systemic mRNA Delivery. Mol Pharm. 2022 Dec 5;19(12):4696-4704. doi: 10.1021/acs.molpharmaceut.2c00738. Epub 2022 Nov 21. PubMed PMID: 36409995; PubMed Central PMCID: PMC9826779.
Demessie AA, Park Y, Singh P, Moses AS, Korzun T, Sabei FY, Albarqi HA, Campos L, Wyatt CR, Farsad K, Dhagat P, Sun C, Taratula OR, Taratula O. An Advanced Thermal Decomposition Method to Produce Magnetic Nanoparticles with Ultrahigh Heating Efficiency for Systemic Magnetic Hyperthermia. Small Methods. 2022 Dec;6(12):e2200916. doi: 10.1002/smtd.202200916. Epub 2022 Nov 1. PubMed PMID: 36319445; PubMed Central PMCID: PMC9772135.
Korzun T, Moses AS, Kim J, Patel S, Schumann C, Levasseur PR, Diba P, Olson B, Rebola KGO, Norgard M, Park Y, Demessie AA, Eygeris Y, Grigoriev V, Sundaram S, Pejovic T, Brody JR, Taratula OR, Zhu X, Sahay G, Marks DL, Taratula O. Nanoparticle-Based Follistatin Messenger RNA Therapy for Reprogramming Metastatic Ovarian Cancer and Ameliorating Cancer-Associated Cachexia. Small. 2022 Nov;18(44):e2204436. doi: 10.1002/smll.202204436. Epub 2022 Sep 13. PubMed PMID: 36098251; PubMed Central PMCID: PMC9633376.
Park Y, Demessie AA, Luo A, Taratula OR, Moses AS, Do P, Campos L, Jahangiri Y, Wyatt CR, Albarqi HA, Farsad K, Slayden OD, Taratula O. Targeted Nanoparticles with High Heating Efficiency for the Treatment of Endometriosis with Systemically Delivered Magnetic Hyperthermia. Small. 2022 Jun;18(24):e2107808. doi: 10.1002/smll.202107808. Epub 2022 Apr 17. PubMed PMID: 35434932; PubMed Central PMCID: PMC9232988.
Mamnoon B, Feng L, Froberg J, Choi Y, Sathish V, Taratula O, Taratula O, Mallik S. Targeting Estrogen Receptor-Positive Breast Microtumors with Endoxifen-Conjugated, Hypoxia-Sensitive Polymersomes. ACS Omega. 2021 Oct 26;6(42):27654-27667. doi: 10.1021/acsomega.1c02250. eCollection 2021 Oct 26. PubMed PMID: 34722965; PubMed Central PMCID: PMC8552235.
Sabei FY, Taratula O, Albarqi HA, Al-Fatease AM, Moses AS, Demessie AA, Park Y, Vogel WK, Esfandiari Nazzaro E, Davare MA, Alani A, Leid M, Taratula O. A targeted combinatorial therapy for Ewing's sarcoma. Nanomedicine. 2021 Oct;37:102446. doi: 10.1016/j.nano.2021.102446. Epub 2021 Jul 23. PubMed PMID: 34303840; PubMed Central PMCID: PMC8464505.
Esfandiari Nazzaro E, Sabei FY, Vogel WK, Nazari M, Nicholson KS, Gafken PR, Taratula O, Taratula O, Davare MA, Leid M. Discovery and Validation of a Compound to Target Ewing's Sarcoma. Pharmaceutics. 2021 Sep 24;13(10). doi: 10.3390/pharmaceutics13101553. PubMed PMID: 34683845; PubMed Central PMCID: PMC8538197.
St Lorenz A, Buabeng ER, Taratula O, Taratula O, Henary M. Near-Infrared Heptamethine Cyanine Dyes for Nanoparticle-Based Photoacoustic Imaging and Photothermal Therapy. J Med Chem. 2021 Jun 24;64(12):8798-8805. doi: 10.1021/acs.jmedchem.1c00771. Epub 2021 Jun 3. PubMed PMID: 34081463; PubMed Central PMCID: PMC10807376.
Moses AS, Demessie AA, Taratula O, Korzun T, Slayden OD, Taratula O. Nanomedicines for Endometriosis: Lessons Learned from Cancer Research. Small. 2021 Feb;17(7):e2004975. doi: 10.1002/smll.202004975. Epub 2021 Jan 25. Review. PubMed PMID: 33491876; PubMed Central PMCID: PMC7928207.
Albarqi HA, Demessie AA, Sabei FY, Moses AS, Hansen MN, Dhagat P, Taratula OR, Taratula O. Systemically Delivered Magnetic Hyperthermia for Prostate Cancer Treatment. Pharmaceutics. 2020 Oct 25;12(11). doi: 10.3390/pharmaceutics12111020. PubMed PMID: 33113767; PubMed Central PMCID: PMC7692290.
Ahoulou EO, Drinkard KK, Basnet K, St Lorenz A, Taratula O, Henary M, Grant KB. DNA Photocleavage in the Near-Infrared Wavelength Range by 2-Quinolinium Dicarbocyanine Dyes. Molecules. 2020 Jun 25;25(12). doi: 10.3390/molecules25122926. PubMed PMID: 32630496; PubMed Central PMCID: PMC7355653.
Han X, Taratula O, Taratula O, Xu K, St Lorenz A, Moses A, Jahangiri Y, Yu G, Farsad K. Biodegradable Hypericin-Containing Nanoparticles for Necrosis Targeting and Fluorescence Imaging. Mol Pharm. 2020 May 4;17(5):1538-1545. doi: 10.1021/acs.molpharmaceut.9b01238. Epub 2020 Apr 7. PubMed PMID: 32212709; PubMed Central PMCID: PMC7341666.
Moses AS, Taratula OR, Lee H, Luo F, Grenz T, Korzun T, Lorenz AS, Sabei FY, Bracha S, Alani AWG, Slayden OD, Taratula O. Nanoparticle-Based Platform for Activatable Fluorescence Imaging and Photothermal Ablation of Endometriosis. Small. 2020 May;16(18):e1906936. doi: 10.1002/smll.201906936. Epub 2020 Apr 6. PubMed PMID: 32250034; PubMed Central PMCID: PMC7210057.
Garbuzenko OB, Kuzmov A, Taratula O, Pine SR, Minko T. Strategy to enhance lung cancer treatment by five essential elements: inhalation delivery, nanotechnology, tumor-receptor targeting, chemo- and gene therapy. Theranostics. 2019;9(26):8362-8376. doi: 10.7150/thno.39816. eCollection 2019. PubMed PMID: 31754402; PubMed Central PMCID: PMC6857061.
Basnet K, Fatemipouya T, St Lorenz A, Nguyen M, Taratula O, Henary M, Grant KB. Single photon DNA photocleavage at 830 nm by quinoline dicarbocyanine dyes. Chem Commun (Camb). 2019 Oct 17;55(84):12667-12670. doi: 10.1039/c9cc04751d. PubMed PMID: 31584046; PubMed Central PMCID: PMC6953408.
Taratula OR, Taratula O, Han X, Jahangiri Y, Tomozawa Y, Horikawa M, Uchida B, Albarqi HA, Schumann C, Bracha S, Korzun T, Farsad K. Transarterial Delivery of a Biodegradable Single-Agent Theranostic Nanoprobe for Liver Tumor Imaging and Combinatorial Phototherapy. J Vasc Interv Radiol. 2019 Sep;30(9):1480-1486.e2. doi: 10.1016/j.jvir.2019.03.004. Epub 2019 Jun 13. PubMed PMID: 31202675; PubMed Central PMCID: PMC7364663.
Majumder J, Taratula O, Minko T. Nanocarrier-based systems for targeted and site specific therapeutic delivery. Adv Drug Deliv Rev. 2019 Apr;144:57-77. doi: 10.1016/j.addr.2019.07.010. Epub 2019 Aug 7. Review. PubMed PMID: 31400350; PubMed Central PMCID: PMC6748653.
Albarqi HA, Wong LH, Schumann C, Sabei FY, Korzun T, Li X, Hansen MN, Dhagat P, Moses AS, Taratula O, Taratula O. Biocompatible Nanoclusters with High Heating Efficiency for Systemically Delivered Magnetic Hyperthermia. ACS Nano. 2019 Jun 25;13(6):6383-6395. doi: 10.1021/acsnano.8b06542. Epub 2019 May 17. PubMed PMID: 31082199; PubMed Central PMCID: PMC6645784.
Schumann C, Nguyen DX, Norgard M, Bortnyak Y, Korzun T, Chan S, Lorenz AS, Moses AS, Albarqi HA, Wong L, Michaelis K, Zhu X, Alani AWG, Taratula OR, Krasnow S, Marks DL, Taratula O. Increasing lean muscle mass in mice via nanoparticle-mediated hepatic delivery of follistatin mRNA. Theranostics. 2018;8(19):5276-5288. doi: 10.7150/thno.27847. eCollection 2018. PubMed PMID: 30555546; PubMed Central PMCID: PMC6276093.
Brady JV, Troyer RM, Ramsey SA, Leeper H, Yang L, Maier CS, Goodall CP, Ruby CE, Albarqi HAM, Taratula O, Bracha S. A Preliminary Proteomic Investigation of Circulating Exosomes and Discovery of Biomarkers Associated with the Progression of Osteosarcoma in a Clinical Model of Spontaneous Disease. Transl Oncol. 2018 Oct;11(5):1137-1146. doi: 10.1016/j.tranon.2018.07.004. Epub 2018 Jul 24. PubMed PMID: 30053712; PubMed Central PMCID: PMC6077151.
Schumann C, Chan S, Millar JA, Bortnyak Y, Carey K, Fedchyk A, Wong L, Korzun T, Moses AS, Lorenz A, Shea D, Taratula O, Khalimonchuk O, Taratula O. Intraperitoneal nanotherapy for metastatic ovarian cancer based on siRNA-mediated suppression of DJ-1 protein combined with a low dose of cisplatin. Nanomedicine. 2018 Jun;14(4):1395-1405. doi: 10.1016/j.nano.2018.03.005. Epub 2018 Apr 7. PubMed PMID: 29635082; PubMed Central PMCID: PMC6174103.
Li X, Schumann C, Albarqi HA, Lee CJ, Alani AWG, Bracha S, Milovancev M, Taratula O, Taratula O. A Tumor-Activatable Theranostic Nanomedicine Platform for NIR Fluorescence-Guided Surgery and Combinatorial Phototherapy. Theranostics. 2018;8(3):767-784. doi: 10.7150/thno.21209. eCollection 2018. PubMed PMID: 29344305; PubMed Central PMCID: PMC5771092.
Duong T, Li X, Yang B, Schumann C, Albarqi HA, Taratula O, Taratula O. Phototheranostic nanoplatform based on a single cyanine dye for image-guided combinatorial phototherapy. Nanomedicine. 2017 Apr;13(3):955-963. doi: 10.1016/j.nano.2016.11.005. Epub 2016 Nov 21. PubMed PMID: 27884637.
Goloviznina NA, Verghese SC, Yoon YM, Taratula O, Marks DL, Kurre P. Mesenchymal stromal cell-derived extracellular vesicles promote myeloid-biased multipotent hematopoietic progenitor expansion via Toll-like receptor engagement. J Biol Chem. 2017 Feb 24;292(8):3541. doi: 10.1074/jbc.A116.745653. PubMed PMID: 28235900; PubMed Central PMCID: PMC5336184.
Li X, Taratula O, Taratula O, Schumann C, Minko T. LHRH-Targeted Drug Delivery Systems for Cancer Therapy. Mini Rev Med Chem. 2017;17(3):258-267. doi: 10.2174/1389557516666161013111155. Review. PubMed PMID: 27739358; PubMed Central PMCID: PMC6645782.
Sapiezynski J, Taratula O, Rodriguez-Rodriguez L, Minko T. Precision targeted therapy of ovarian cancer. J Control Release. 2016 Dec 10;243:250-268. doi: 10.1016/j.jconrel.2016.10.014. Epub 2016 Oct 14. Review. PubMed PMID: 27746277; PubMed Central PMCID: PMC5191987.
Goloviznina NA, Verghese SC, Yoon YM, Taratula O, Marks DL, Kurre P. Mesenchymal Stromal Cell-derived Extracellular Vesicles Promote Myeloid-biased Multipotent Hematopoietic Progenitor Expansion via Toll-Like Receptor Engagement. J Biol Chem. 2016 Nov 18;291(47):24607-24617. doi: 10.1074/jbc.M116.745653. Epub 2016 Oct 7. PubMed PMID: 27758863; PubMed Central PMCID: PMC5114412.
Schumann C, Chan S, Khalimonchuk O, Khal S, Moskal V, Shah V, Alani AW, Taratula O, Taratula O. Mechanistic Nanotherapeutic Approach Based on siRNA-Mediated DJ-1 Protein Suppression for Platinum-Resistant Ovarian Cancer. Mol Pharm. 2016 Jun 6;13(6):2070-83. doi: 10.1021/acs.molpharmaceut.6b00205. Epub 2016 May 26. PubMed PMID: 27170529; PubMed Central PMCID: PMC5332073.
Schumann C, Taratula O, Khalimonchuk O, Palmer AL, Cronk LM, Jones CV, Escalante CA, Taratula O. ROS-induced nanotherapeutic approach for ovarian cancer treatment based on the combinatorial effect of photodynamic therapy and DJ-1 gene suppression. Nanomedicine. 2015 Nov;11(8):1961-70. doi: 10.1016/j.nano.2015.07.005. Epub 2015 Jul 31. PubMed PMID: 26238076.
Taratula O, Patel M, Schumann C, Naleway MA, Pang AJ, He H, Taratula O. Phthalocyanine-loaded graphene nanoplatform for imaging-guided combinatorial phototherapy. Int J Nanomedicine. 2015;10:2347-62. doi: 10.2147/IJN.S81097. eCollection 2015. PubMed PMID: 25848255; PubMed Central PMCID: PMC4378304.
Taratula O, Schumann C, Duong T, Taylor KL, Taratula O. Dendrimer-encapsulated naphthalocyanine as a single agent-based theranostic nanoplatform for near-infrared fluorescence imaging and combinatorial anticancer phototherapy. Nanoscale. 2015 Mar 7;7(9):3888-902. doi: 10.1039/c4nr06050d. PubMed PMID: 25422147.
Dani RK, Schumann C, Taratula O, Taratula O. Temperature-tunable iron oxide nanoparticles for remote-controlled drug release. AAPS PharmSciTech. 2014 Aug;15(4):963-72. doi: 10.1208/s12249-014-0131-x. Epub 2014 May 13. PubMed PMID: 24821220; PubMed Central PMCID: PMC4113623.
Garbuzenko OB, Mainelis G, Taratula O, Minko T. Inhalation treatment of lung cancer: the influence of composition, size and shape of nanocarriers on their lung accumulation and retention. Cancer Biol Med. 2014 Mar;11(1):44-55. doi: 10.7497/j.issn.2095-3941.2014.01.004. PubMed PMID: 24738038; PubMed Central PMCID: PMC3969800.
Taratula O, Dani RK, Schumann C, Xu H, Wang A, Song H, Dhagat P, Taratula O. Multifunctional nanomedicine platform for concurrent delivery of chemotherapeutic drugs and mild hyperthermia to ovarian cancer cells. Int J Pharm. 2013 Dec 15;458(1):169-80. doi: 10.1016/j.ijpharm.2013.09.032. Epub 2013 Oct 1. PubMed PMID: 24091153.
Shah V, Taratula O, Garbuzenko OB, Taratula OR, Rodriguez-Rodriguez L, Minko T. Targeted nanomedicine for suppression of CD44 and simultaneous cell death induction in ovarian cancer: an optimal delivery of siRNA and anticancer drug. Clin Cancer Res. 2013 Nov 15;19(22):6193-204. doi: 10.1158/1078-0432.CCR-13-1536. Epub 2013 Sep 13. PubMed PMID: 24036854; PubMed Central PMCID: PMC3846837.
Taratula O, Kuzmov A, Shah M, Garbuzenko OB, Minko T. Nanostructured lipid carriers as multifunctional nanomedicine platform for pulmonary co-delivery of anticancer drugs and siRNA. J Control Release. 2013 Nov 10;171(3):349-57. doi: 10.1016/j.jconrel.2013.04.018. Epub 2013 May 3. PubMed PMID: 23648833; PubMed Central PMCID: PMC3766401.
Taratula O, Schumann C, Naleway MA, Pang AJ, Chon KJ, Taratula O. A multifunctional theranostic platform based on phthalocyanine-loaded dendrimer for image-guided drug delivery and photodynamic therapy. Mol Pharm. 2013 Oct 7;10(10):3946-58. doi: 10.1021/mp400397t. Epub 2013 Sep 10. PubMed PMID: 24020847.
Shah V, Taratula O, Garbuzenko OB, Patil ML, Savla R, Zhang M, Minko T. Genotoxicity of different nanocarriers: possible modifications for the delivery of nucleic acids. Curr Drug Discov Technol. 2013 Mar;10(1):8-15. PubMed PMID: 22564170; PubMed Central PMCID: PMC3899095.
Chen AM, Taratula O, Wei D, Yen HI, Thomas T, Thomas TJ, Minko T, He H. Labile catalytic packaging of DNA/siRNA: control of gold nanoparticles "out" of DNA/siRNA complexes. ACS Nano. 2010 Jul 27;4(7):3679-88. doi: 10.1021/nn901796n. PubMed PMID: 20521827; PubMed Central PMCID: PMC2919656.
Taratula O, Garbuzenko OB, Kirkpatrick P, Pandya I, Savla R, Pozharov VP, He H, Minko T. Surface-engineered targeted PPI dendrimer for efficient intracellular and intratumoral siRNA delivery. J Control Release. 2009 Dec 16;140(3):284-93. doi: 10.1016/j.jconrel.2009.06.019. Epub 2009 Jun 28. PubMed PMID: 19567257; PubMed Central PMCID: PMC2787988.
Chen AM, Zhang M, Wei D, Stueber D, Taratula O, Minko T, He H. Co-delivery of doxorubicin and Bcl-2 siRNA by mesoporous silica nanoparticles enhances the efficacy of chemotherapy in multidrug-resistant cancer cells. Small. 2009 Dec;5(23):2673-7. doi: 10.1002/smll.200900621. PubMed PMID: 19780069; PubMed Central PMCID: PMC2833276.
Xiao Y, Gao X, Taratula O, Treado S, Urbas A, Holbrook RD, Cavicchi RE, Avedisian CT, Mitra S, Savla R, Wagner PD, Srivastava S, He H. Anti-HER2 IgY antibody-functionalized single-walled carbon nanotubes for detection and selective destruction of breast cancer cells. BMC Cancer. 2009 Oct 2;9:351. doi: 10.1186/1471-2407-9-351. PubMed PMID: 19799784; PubMed Central PMCID: PMC2764730.
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