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Dreier MR, Walia J, de la Serna IL. Targeting SWI/SNF Complexes in Cancer: Pharmacological Approaches and Implications. Epigenomes. 2024 Feb 4;8(1). doi: 10.3390/epigenomes8010007. Review. PubMed PMID: 38390898; PubMed Central PMCID: PMC10885108.
Ahmad N, de la Serna IL, Marathe HG, Fan X, Dube P, Zhang S, Haller ST, Kennedy DJ, Pestov NB, Modyanov NN. Eutherian-Specific Functions of BetaM Acquired through Atp1b4 Gene Co-Option in the Regulation of MyoD Expression. Life (Basel). 2023 Feb 2;13(2). doi: 10.3390/life13020414. PubMed PMID: 36836771; PubMed Central PMCID: PMC9962273.
Basuroy T, Dreier M, Baum C, Blomquist T, Trumbly R, Filipp FV, de la Serna IL. Epigenetic and pharmacological control of pigmentation via Bromodomain Protein 9 (BRD9). Pigment Cell Melanoma Res. 2023 Jan;36(1):19-32. doi: 10.1111/pcmr.13068. Epub 2022 Oct 3. PubMed PMID: 36112085; PubMed Central PMCID: PMC10091956.
Dreier MR, de la Serna IL. SWI/SNF Chromatin Remodeling Enzymes in Melanoma. Epigenomes. 2022 Mar 18;6(1). doi: 10.3390/epigenomes6010010. Review. PubMed PMID: 35323214; PubMed Central PMCID: PMC8947417.
Subramaniyan B, Sridharan S, M Howard C, M C Tilley A, Basuroy T, de la Serna I, Butt E, Raman D. Role of the CXCR4-LASP1 Axis in the Stabilization of Snail1 in Triple-Negative Breast Cancer. Cancers (Basel). 2020 Aug 21;12(9). doi: 10.3390/cancers12092372. PubMed PMID: 32825729; PubMed Central PMCID: PMC7563118.
Trivedi A, Mehrotra A, Baum CE, Lewis B, Basuroy T, Blomquist T, Trumbly R, Filipp FV, Setaluri V, de la Serna IL. Bromodomain and extra-terminal domain (BET) proteins regulate melanocyte differentiation. Epigenetics Chromatin. 2020 Mar 10;13(1):14. doi: 10.1186/s13072-020-00333-z. PubMed PMID: 32151278; PubMed Central PMCID: PMC7063807.
Basuroy T, de la Serna IL. SETD7 in cardiomyocyte differentiation and cardiac function. Stem Cell Investig. 2019;6:29. doi: 10.21037/sci.2019.08.01. eCollection 2019. PubMed PMID: 31620476; PubMed Central PMCID: PMC6789293.
Aras S, Saladi SV, Basuroy T, Marathe HG, Lorès P, de la Serna IL. BAF60A mediates interactions between the microphthalmia-associated transcription factor and the BRG1-containing SWI/SNF complex during melanocyte differentiation. J Cell Physiol. 2019 Jul;234(7):11780-11791. doi: 10.1002/jcp.27840. Epub 2018 Dec 4. PubMed PMID: 30515787; PubMed Central PMCID: PMC6426657.
Datar I, Kalpana G, Choi J, Basuroy T, Trumbly R, Chaitanya Arudra SK, McPhee MD, de la Serna I, Yeung KC. Critical role of miR-10b in B-RafV600E dependent anchorage independent growth and invasion of melanoma cells. PLoS One. 2019;14(4):e0204387. doi: 10.1371/journal.pone.0204387. eCollection 2019. PubMed PMID: 30995246; PubMed Central PMCID: PMC6469749.
Marathe HG, Watkins-Chow DE, Weider M, Hoffmann A, Mehta G, Trivedi A, Aras S, Basuroy T, Mehrotra A, Bennett DC, Wegner M, Pavan WJ, de la Serna IL. BRG1 interacts with SOX10 to establish the melanocyte lineage and to promote differentiation. Nucleic Acids Res. 2017 Jun 20;45(11):6442-6458. doi: 10.1093/nar/gkx259. PubMed PMID: 28431046; PubMed Central PMCID: PMC5499657.
Datar I, Qiu X, Ma HZ, Yeung M, Aras S, de la Serna I, Al-Mulla F, Tan TZ, Thiery JP, Trumbly R, Xuan F, Cui H, Yeung KC. Correction: RKIP regulates CCL5 expression to inhibit breast cancer invasion and metastasis by controlling macrophage infiltration. Oncotarget. 2016 May 3;7(18):26925. doi: 10.18632/oncotarget.9139. PubMed PMID: 27532884; PubMed Central PMCID: PMC5042026.
Datar I, Qiu X, Ma HZ, Yeung M, Aras S, de la Serna I, Al-Mulla F, Thiery JP, Trumbly R, Fan X, Cui H, Yeung KC. RKIP regulates CCL5 expression to inhibit breast cancer invasion and metastasis by controlling macrophage infiltration. Oncotarget. 2015 Nov 17;6(36):39050-61. doi: 10.18632/oncotarget.5176. PubMed PMID: 26375811; PubMed Central PMCID: PMC4770756.
Mehta G, Kumarasamy S, Wu J, Walsh A, Liu L, Williams K, Joe B, de la Serna IL. MITF interacts with the SWI/SNF subunit, BRG1, to promote GATA4 expression in cardiac hypertrophy. J Mol Cell Cardiol. 2015 Nov;88:101-10. doi: 10.1016/j.yjmcc.2015.09.010. Epub 2015 Sep 24. PubMed PMID: 26388265; PubMed Central PMCID: PMC4640968.
Datar I, Feng J, Qiu X, Lewandowski J, Yeung M, Ren G, Aras S, Al-Mulla F, Cui H, Trumbly R, Arudra SK, De Las Casas LE, de la Serna I, Bitar MS, Yeung KC. RKIP Inhibits Local Breast Cancer Invasion by Antagonizing the Transcriptional Activation of MMP13. PLoS One. 2015;10(8):e0134494. doi: 10.1371/journal.pone.0134494. eCollection 2015. PubMed PMID: 26308852; PubMed Central PMCID: PMC4550449.
Mehrotra A, Saladi SV, Trivedi AR, Aras S, Qi H, Jayanthy A, Setaluri V, de la Serna IL. Modulation of Brahma expression by the mitogen-activated protein kinase/extracellular signal regulated kinase pathway is associated with changes in melanoma proliferation. Arch Biochem Biophys. 2014 Dec 1;563:125-35. doi: 10.1016/j.abb.2014.07.004. Epub 2014 Jul 12. PubMed PMID: 25026375; PubMed Central PMCID: PMC4221548.
Mehrotra A, Mehta G, Aras S, Trivedi A, de la Serna IL. SWI/SNF chromatin remodeling enzymes in melanocyte differentiation and melanoma. Crit Rev Eukaryot Gene Expr. 2014;24(2):151-61. doi: 10.1615/critreveukaryotgeneexpr.2014007882. Review. PubMed PMID: 24940768; PubMed Central PMCID: PMC4104388.
Mehrotra A, Joe B, de la Serna IL. SWI/SNF chromatin remodeling enzymes are associated with cardiac hypertrophy in a genetic rat model of hypertension. J Cell Physiol. 2013 Dec;228(12):2337-42. doi: 10.1002/jcp.24404. PubMed PMID: 23702776; PubMed Central PMCID: PMC4040522.
Marathe HG, Mehta G, Zhang X, Datar I, Mehrotra A, Yeung KC, de la Serna IL. SWI/SNF enzymes promote SOX10- mediated activation of myelin gene expression. PLoS One. 2013;8(7):e69037. doi: 10.1371/journal.pone.0069037. Print 2013. PubMed PMID: 23874858; PubMed Central PMCID: PMC3712992.
Blomquist TM, Brown RD, Crawford EL, de la Serna I, Williams K, Yoon Y, Hernandez DA, Willey JC. CEBPG Exhibits Allele-Specific Expression in Human Bronchial Epithelial Cells. Gene Regul Syst Bio. 2013;7:125-38. doi: 10.4137/GRSB.S11879. Print 2013. PubMed PMID: 23888109; PubMed Central PMCID: PMC3712557.
Saladi SV, Wong PG, Trivedi AR, Marathe HG, Keenen B, Aras S, Liew ZQ, Setaluri V, de la Serna IL. BRG1 promotes survival of UV-irradiated melanoma cells by cooperating with MITF to activate the melanoma inhibitor of apoptosis gene. Pigment Cell Melanoma Res. 2013 May;26(3):377-91. doi: 10.1111/pcmr.12088. Epub 2013 Apr 2. PubMed PMID: 23480510; PubMed Central PMCID: PMC3633630.
Ren G, Baritaki S, Marathe H, Feng J, Park S, Beach S, Bazeley PS, Beshir AB, Fenteany G, Mehra R, Daignault S, Al-Mulla F, Keller E, Bonavida B, de la Serna I, Yeung KC. Polycomb protein EZH2 regulates tumor invasion via the transcriptional repression of the metastasis suppressor RKIP in breast and prostate cancer. Cancer Res. 2012 Jun 15;72(12):3091-104. doi: 10.1158/0008-5472.CAN-11-3546. Epub 2012 Apr 13. PubMed PMID: 22505648; NIHMSID:NIHMS371335.
Ren G, Feng J, Datar I, Yeung AH, Saladi SV, Feng Y, de la Serna I, Yeung KC. A Micro-RNA Connection in BRaf(V600E)-Mediated Premature Senescence of Human Melanocytes. Int J Cell Biol. 2012;2012:913242. doi: 10.1155/2012/913242. Epub 2012 Apr 24. PubMed PMID: 22611400; PubMed Central PMCID: PMC3348633.
Saladi SV, Keenen B, Marathe HG, Qi H, Chin KV, de la Serna IL. Modulation of extracellular matrix/adhesion molecule expression by BRG1 is associated with increased melanoma invasiveness. Mol Cancer. 2010 Oct 22;9:280. doi: 10.1186/1476-4598-9-280. PubMed PMID: 20969766; PubMed Central PMCID: PMC3098014.
Wu Q, Saunders RA, Szkudlarek-Mikho M, Serna Ide L, Chin KV. The obesity-associated Fto gene is a transcriptional coactivator. Biochem Biophys Res Commun. 2010 Oct 22;401(3):390-5. doi: 10.1016/j.bbrc.2010.09.064. Epub 2010 Sep 19. PubMed PMID: 20858458; PubMed Central PMCID: PMC2963669.
Vinod Saladi S, Marathe H, de la Serna IL. SWItching on the transcriptional circuitry in melanoma. Epigenetics. 2010 Aug 16;5(6):469-75. doi: 10.4161/epi.5.6.12315. Epub 2010 Aug 16. Review. PubMed PMID: 20543574; PubMed Central PMCID: PMC3230549.
Saladi SV, de la Serna IL. ATP dependent chromatin remodeling enzymes in embryonic stem cells. Stem Cell Rev Rep. 2010 Mar;6(1):62-73. doi: 10.1007/s12015-010-9120-y. Review. PubMed PMID: 20148317; PubMed Central PMCID: PMC2862992.
Keenen B, Qi H, Saladi SV, Yeung M, de la Serna IL. Heterogeneous SWI/SNF chromatin remodeling complexes promote expression of microphthalmia-associated transcription factor target genes in melanoma. Oncogene. 2010 Jan 7;29(1):81-92. doi: 10.1038/onc.2009.304. Epub 2009 Sep 28. PubMed PMID: 19784067; PubMed Central PMCID: PMC2803337.
Keenen B, de la Serna IL. Chromatin remodeling in embryonic stem cells: regulating the balance between pluripotency and differentiation. J Cell Physiol. 2009 Apr;219(1):1-7. doi: 10.1002/jcp.21654. Review. PubMed PMID: 19097034.
de la Serna IL, Ohkawa Y, Higashi C, Dutta C, Osias J, Kommajosyula N, Tachibana T, Imbalzano AN. The microphthalmia-associated transcription factor requires SWI/SNF enzymes to activate melanocyte-specific genes. J Biol Chem. 2006 Jul 21;281(29):20233-41. doi: 10.1074/jbc.M512052200. Epub 2006 Apr 28. PubMed PMID: 16648630.
de la Serna IL, Ohkawa Y, Imbalzano AN. Chromatin remodelling in mammalian differentiation: lessons from ATP-dependent remodellers. Nat Rev Genet. 2006 Jun;7(6):461-73. doi: 10.1038/nrg1882. Review. PubMed PMID: 16708073.
de la Serna IL, Ohkawa Y, Berkes CA, Bergstrom DA, Dacwag CS, Tapscott SJ, Imbalzano AN. MyoD targets chromatin remodeling complexes to the myogenin locus prior to forming a stable DNA-bound complex. Mol Cell Biol. 2005 May;25(10):3997-4009. doi: 10.1128/MCB.25.10.3997-4009.2005. PubMed PMID: 15870273; PubMed Central PMCID: PMC1087700.
Hill DA, de la Serna IL, Veal TM, Imbalzano AN. BRCA1 interacts with dominant negative SWI/SNF enzymes without affecting homologous recombination or radiation-induced gene activation of p21 or Mdm2. J Cell Biochem. 2004 Apr 1;91(5):987-98. doi: 10.1002/jcb.20003. PubMed PMID: 15034933.
Moen PT Jr, Johnson CV, Byron M, Shopland LS, de la Serna IL, Imbalzano AN, Lawrence JB. Repositioning of muscle-specific genes relative to the periphery of SC-35 domains during skeletal myogenesis. Mol Biol Cell. 2004 Jan;15(1):197-206. doi: 10.1091/mbc.e03-06-0388. Epub 2003 Nov 14. PubMed PMID: 14617810; PubMed Central PMCID: PMC307540.
de la Serna IL, Imbalzano AN. Unfolding heterochromatin for replication. Nat Genet. 2002 Dec;32(4):560-2. doi: 10.1038/ng1202-560. PubMed PMID: 12457187.
Roy K, de la Serna IL, Imbalzano AN. The myogenic basic helix-loop-helix family of transcription factors shows similar requirements for SWI/SNF chromatin remodeling enzymes during muscle differentiation in culture. J Biol Chem. 2002 Sep 13;277(37):33818-24. doi: 10.1074/jbc.M205159200. Epub 2002 Jul 8. PubMed PMID: 12105204.
de la Serna IL, Roy K, Carlson KA, Imbalzano AN. MyoD can induce cell cycle arrest but not muscle differentiation in the presence of dominant negative SWI/SNF chromatin remodeling enzymes. J Biol Chem. 2001 Nov 2;276(44):41486-91. doi: 10.1074/jbc.M107281200. Epub 2001 Aug 24. PubMed PMID: 11522799.
de la Serna IL, Carlson KA, Imbalzano AN. Mammalian SWI/SNF complexes promote MyoD-mediated muscle differentiation. Nat Genet. 2001 Feb;27(2):187-90. doi: 10.1038/84826. PubMed PMID: 11175787.
de la Serna I, Cujec TP, Shi Y, Tyler BM. Non-coordinate regulation of 5S rRNA genes and the gene encoding the 5S rRNA-binding ribosomal protein homolog in Neurospora crassa. Mol Gen Genet. 2000 Jul;263(6):987-94. doi: 10.1007/pl00008699. PubMed PMID: 10954084.
de La Serna IL, Carlson KA, Hill DA, Guidi CJ, Stephenson RO, Sif S, Kingston RE, Imbalzano AN. Mammalian SWI-SNF complexes contribute to activation of the hsp70 gene. Mol Cell Biol. 2000 Apr;20(8):2839-51. doi: 10.1128/MCB.20.8.2839-2851.2000. PubMed PMID: 10733587; PubMed Central PMCID: PMC85505.
de la Serna I, Ng D, Tyler BM. Carbon regulation of ribosomal genes in Neurospora crassa occurs by a mechanism which does not require Cre-1, the homologue of the Aspergillus carbon catabolite repressor, CreA. Fungal Genet Biol. 1999 Apr;26(3):253-69. doi: 10.1006/fgbi.1999.1121. PubMed PMID: 10361038.
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