Modeling collective cell behavior in cancer: Perspectives from an interdisciplinary conversation

Affiliations

• ¹ Department of Mathematics, University of Utah, Salt Lake City, UT 84112, USA; School of Biological Sciences, University of Utah, Salt Lake City, UT 84112, USA.
• ² Integrated Mathematical Oncology Department, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.
• ³ Department of Biomedical Engineering, Illinois Institute of Technology, Chicago, IL 60616, USA.
• ⁴ Ming Hsieh Department of Electrical and Computer Engineering, Viterbi School of Engineering, University of Southern California, Los Angeles, CA 90089, USA.
• ⁵ Division of Hematology and Oncology, Department of Medicine, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
• ⁶ Department of Biomedical Engineering, The University of Texas at Austin, Austin, TX 78712, USA.
• ⁷ Department of Mechanical Engineering, Johns Hopkins University, Baltimore, MD 21218, USA.
• ⁸ Cancer Signaling and Microenvironment Program, Marvin and Concetta Greenberg Pancreatic Cancer Institute, Fox Chase Cancer Center, Philadelphia, PA 19111, USA; Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19140, USA.
• ⁹ Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN 37232, USA.
• ¹⁰ Boston University-Boston Medical Center Cancer Center, Boston University School of Medicine, Boston, MA 02118, USA.
• ¹¹ J. Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, FL 32611, USA; University of Florida Health Cancer Center, University of Florida, Gainesville, FL 32611, USA.
• ¹² Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA 94158, USA; NSF Center for Cellular Construction, San Francisco, CA 94158, USA; Chan Zuckerberg Biohub, San Francisco, CA 94158, USA.
• ¹³ Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
• ¹⁴ Department of Biology, Stanford University, Stanford, CA 94305, USA.
• ¹⁵ Department of Biology, Clarkson University, Potsdam, NY 13699, USA.
• ¹⁶ Centre for BioSystems Science and Engineering, Indian Institute of Science, Bangalore, 560012, India.
• ¹⁷ Department of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
• ¹⁸ Department of Pathology, The University of Alabama at Birmingham, Birmingham, AL 35294, USA; O'Neal Comprehensive Cancer Center, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.
• ¹⁹ Mechanical Engineering Department, San Diego State University, San Diego, CA 92182, USA; Computational Sciences Research Center, San Diego State University, San Diego, CA 92182, USA.
• ²⁰ Department of Dermatology, Oregon Health and Science University, Portland, OR 97239, USA; Department Biomedical Engineering, Oregon Health and Science University, Portland, OR 97239, USA; Department Oncological Sciences, Knight Cancer Institute, Oregon Health and Science University, Portland, OR 97239, USA; Cancer Early Detection Advanced Research Center (CEDAR), Knight Cancer Institute, Oregon Health and Science University, Portland, OR 97239, USA; Operative Care Division, VA Portland Health Care System, Portland, OR 97239, USA.
• ²¹ Department of Cell and Tissue Biology, University of California, San Francisco, San Francisco, CA 94143, USA.
• ²² Department of Developmental and Cell Biology, University of California, Irvine, Irvine, CA 92697, USA; Center for Complex Biological Systems, University of California, Irvine, Irvine, CA 92697, USA.
• ²³ Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY 10021, USA; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY 10021, USA; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10021, USA.
• ²⁴ Center for Theoretical Biological Physics, Northeastern University, Boston, MA 02115, USA.
• ²⁵ Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.
• ²⁶ Department of Neurosurgery, Rogel Cancer Center, The University of Michigan, Ann Arbor, MI 48109, USA; Department of Cell and Developmental Biology, Rogel Cancer Center, The University of Michigan, Ann Arbor, MI 48109, USA; Department of Biomedical Engineering, The University of Michigan, Ann Arbor, MI 48109, USA.
• ²⁷ Department of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI 53706, USA.
• ²⁸ Computational and Systems Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Howard Hughes Medical Institute, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
• ²⁹ Department of Chemical Engineering, University of Massachusetts, Amherst, MA 01003, USA.
• ³⁰ Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Emory University, Atlanta, GA 30322, USA; Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Emory University, Atlanta, GA 30322, USA.
• ³¹ Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
• ³² Department of Molecular and Cellular Biology, University of California, Davis, Davis, CA 95616, USA.
• ³³ Department of Pathology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA; University of Colorado Cancer Center, Aurora, CO 80045, USA.
• ³⁴ Department of Biology, The University of Alabama at Birmingham, Birmingham, AL 35294, USA.
• ³⁵ Department of Neurosurgery, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
• ³⁶ Department of Surgery, Duke University, Durham, NC 27710, USA; Department of Cell Biology, Duke University, Durham, NC 27710, USA.
• ³⁷ Allen Institute for Immunology, Seattle, WA 98109, USA; Seagen, Bothell, WA 98021, USA.
• ³⁸ Department of Electrical Engineering and Computer Sciences, University of California, Berkeley, Berkeley, CA 94720, USA.
• ³⁹ Perlmutter Cancer Center, NYU School of Medicine, New York, NY 10016, USA; Institute for Computational Medicine, NYU Langone Health, New York, NY 10016, USA.
• ⁴⁰ Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15232, USA; Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA 15232, USA.
• ⁴¹ Division of Cancer Biology, National Cancer Institute, National Institutes of Health, Rockville, MD 20850, USA. Electronic address: hannah.dueck@nih.gov.