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Welcome:

Welcome to the Jiang lab on systems immunology. A dysfunctional or dysregulated immune system not only fails to offer protection, it can also introduce unnecessary immune responses such as allergies or autoimmune diseases. The key to immune modulation and engineering and regenerative medicine is to understand how the normal immune system works. However, a full understanding of the complex interactions among immune cells and between immune cells and cytokines and chemokines requires a quantitative and systems approach. Using high-throughput sequencing and single-cell analysis in combination with quantitative analysis, we are interested in answering the following questions: How does the immune system develop and age? What are the molecular signatures of autoimmune diseases? Why does the immune system tolerate tumors? Answers to these questions are important in establishing metrics for immune health and providing biomarkers for diagnosis and therapy.

Group Photo

News & Events:

Postdoctoral Fellow and Graduate Research Assistant Positions Available

Postdoctoral fellow and graduate student research assistant positions are available in the genomics, computational biology, and immunology.

Interested applicants should forward by e-mail a cover letter, curriculum vitae, and the names, telephone numbers and e-mail addresses of three references to:

Ning Jenny Jiang, Ph.D.
Department of Bioengineering
University of Pennsylvania
Philadelphia, PA 19104


Check out our most recent work published in Nature Immunology!

Guo Y, High-throughput and high-dimensional single-cell analysis of antigen-specific CD8+ T cells from JRNLclub on Vimeo.

Jun 1, 2021 The Jiang Lab has moved from the University of Texas at Austin to the University of Pennsylvania!

Jan 13, 2021 Dr. Jiang was invited to present at the Chan Zuckerberg Initiative Inflammation Networks monthly webinar series.

Jan 6-9, 2021 Dr. Jiang was invited to give a talk at the 11th International Conference on Biomolecular Engineering (ICBE 2021)

Oct 14, 2020 Dr. Jiang chaired a session for the Micro and Nano Technologies in Diagnostics at BMES 2020

Aug 5, 2020 Welcome new graduate student, Shahab (Shawn) Chizari, to the lab. Shawn is a first year Biomedical Engineering student. He graduated from UC Davis.

Jul 17, 2020 Ben Wendel's antibody repertoire sequencing analysis of rapid HIV progressors was published in (Journal of Immunology). Congratulations!

Apr 28, 2020 Dr. Jiang was invited to give a departmental seminar in the Department of Hematopoietic Biology and Malignancy at MD Anderson Cancer Center.

Apr 23, 2020 Dr. Jiang gave an invited talk at the Frontiers in Bioengineering Research webinar series organized by the Department of Bioengineering at Rice University.

Apr 9, 2020 Dr. Jiang was elected to the Council of Cellular and Molecular Bioengineering Significant Interest Group of Biomedical Engineering Society. Congratulations!

Feb 3, 2020 Dr. Jiang gave an invited talk at the Keystone Symposia on Antibodies as Drugs: From B Cell Biology to New Treatments in Santa Fe, New Mexico.

Jan 24, 2020 Dr. Jiang was invited to give a departmental seminar in the Department of Bioengineering at Rice University.

Jan 9, 2020 Dr. Jiang was invited to give a departmental seminar in the Department of Bioengineering at University of Pennsylvania.

Jan 5, 2020 Dr. Jiang gave an invited talk at the 2020 Cellular and Molecular Bioengineering Conference in Puerto Rico!

Oct 31, 2019 Welcome new graduate student, Jack Prazich, to the lab. Jack is a first year Biomedical Engineering student. He graduated from University of Wisconsin-Madison.

Oct 28, 2019 Dr. Jiang was invited to give a departmental seminar in the Department Biomedical Engineering at the University of Florida.

Oct 23, 2019 We are grateful that Chan Zuckerberg Initiative has funded our proposal on Building Neurodegeneration Community at UT Austin, which is led Mae Lewis in the lab. Congratulations Mae!

Oct 19, 2019 Congratulations to Dr. Jiang, who successfully organized the Cellular and Molecular Bioengineering track for Biomedical Engineering Society Annual meeting, BMES 2019!

Oct 17, 2019 Congratulations to Alexandra Schonnesen, who just delivered a fantastic talk at the 2019 Biomedical Engineering Society Annual meeting!

Oct 4, 2019 Welcome new graduate student, Yuwan Guo, to the lab. Yuwan is a first year Chemical Engineering student. She graduated from UCLA.

Sep 21, 2019 Dr. Jiang was invited to present at the 2019 International Conference on Biomechanics and Medical Engineering - Y.C. Fung 100th Birthday Celebration session

July 22, 2019 Dr. Jiang was invited to present at the 7th Sino-American Workshop on Biomedical Engineering and Biomechanics in Chongqing, China

July 17, 2019 Dr. Jiang was invited to participate the National Academy of Medicine Emerging Leaders Forum, Washington, D.C.

Jun 25, 2019 Dr. Jiang was invited to present at the 2019 Summer Biomechanics, Bioengineering and Biotransport Conference YC Fung 100th Birthday Symposium.

May 23, 2019 Congratulations to Dr. Jiang, who was selected as one of ten National Academy of Medicine's Emerging Leaders in Health and Medicine Scholars! She was also invited to attend the NAM Emerging Leaders Forum to be held at Washington DC in July. Read more on UT Austin's news.

May 6, 2019 Dr. Jiang was invited to give a talk at the 1st Synthetic and Systems Immunology Conference 2019 that was held at beautiful Ascona, Switzerland.

Mar 14, 2019 Congratulations to Dr. Jiang, who was invited to give a talk at the Cold Spring Harbor meeting on Systems Immunology!

Mar 1, 2019 Congratulations to alumnus, Ben Wendel, who was awarded the prestigious A.P. Giannini Foundation Postdoctoral Fellowship ! Way to go Ben!

Feb 26, 2019 Congratulations to Dr. Jiang, who participated the Chan Zuckerberg Initiative Neurodegenerative disease challenge network kick off meeting. Listening to patient advocates talking about the impact of various neurodegenerative diseases have on their lives and how they turned from regular patients to patient advocates motivated Dr. Jiang to develop cutting edge systems immunological tools to help disease early diagnosis and to engineer new therapeutics.

Feb 21, 2019 Congratulations to Kevin whose paper on analyzing cancer antigen expression pattern in single cells was published by JCI insight . Kevin for sure likes the idea of analyzing other's data :).

Feb 5, 2019 Congratulations to Dr. Jiang, Alex, and Kevin! There review paper on T cell repertoire profiling in cancer was published in Trends in Cancer .

Jan 13, 2019 Congratulations to Kevin who was invited to give a talk on TetTCR-Seq at the Keystone Symposia on Single Cell Biology held at Breckenridge, CO! At the same time, Kevin was also selected to receive the Keystone Symposia Future of Science Fund scholarship for attending the meeting. Congratulations to Kevin and hope you enjoyed skiing!

Dec 12, 2018 Congratulations to Kevin who received both travel awards from the Institute of Cellular and Molecular Biology and the Center for Molecular Carcinogenesis and Toxicology!

Dec 5, 2018 Dr. Jiang was selected to receive the prestigious Chan Zuckerberg Initiative Neurodegeneration Challenge Network Ben Barres Early Career Acceleration awards

Congratulations! Read more on UT News here.

Nov 12, 2018 Our paper on TetTCR-Seq is on Nature Biotechnology online advanced publications. Congratulations to Shuqi, Kevin, Alex, and Mingliang! Read more on UT News here.

For all news, please click here